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The CAPRISA Clinical Trials: HIV Treatment and Prevention

Since its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA's high... Celý popis

Instituce: Tomas Bata University
Korporativní autor: SpringerLink (Online service)
Další autoři: Abdool Karim, Quarraisha., Abdool Karim, Salim S., Baxter, Cheryl.
Médium: E-kniha
Jazyk: English
Vydáno: Cham : Springer International Publishing : 2017
Témata:
Medicine.
Health promotion.
Health informatics.
Infectious diseases.
elektronické knihy
electronic books
On-line přístup: https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-47518-9
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Obsah:
  • Part I. Introduction
  • Studies Linked to the Evolving HIV Epidemic in South Africa: Informing the CAPRISA Scientific Agenda
  • CAPRISA: Establishing A Research Center to Undertake HIV Clinical Trials
  • Overview of Clinical Trials
  • Part II. CAPRISA Clinical Trials for HIV and HSV-2 Prevention
  • Antiretrovirals for HIV Prevention
  • Rolling out of tenofovir gel in family planning clinics: the CAPRISA 008 implementation trial
  • Conditional cash transfers to reduce HIV risk in young women: the CAPRISA 007 cluster randomised control trial
  • HIV vaccine and passive immunity trials
  • Part III: CAPRISA Clinical Trials for HIV-TB Treatment
  • CAPRISA 003: Timing of antiretroviral initiation in HIV-TB co-infected patients - The SAPiT Trial
  • Scaling up TB-HIV integration in public health clinics: translating research findings into practice
  • Part IV: Experiences and lessons learnt from clinical trials in CAPRISA
  • Lessons from the Acute Infection Study: from Bench to Bedside
  • Understanding sexual HIV transmission in women by focusing on the genital mucosa
  • Part V: Essential support activities for the conduct of clinical trials
  • Good practices in conducting clinical trials: Good Participatory Practice, Good Pharmacy Practice and Good Laboratory Practice
  • Grants Management
  • Taking science to the people: communication and media strategies for clinical trials
  • Looking ahead: What Does the Future Hold for CAPRISA?
  • Appendix
  • Index. .

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