Natural product chemistry for drug discovery
| Instituce: | Tomas Bata University |
|---|---|
| Další autoři: | Buss, Antony D., Butler, Mark S. |
| Médium: | E-kniha |
| Jazyk: | English |
| Vydáno: |
Cambridge : RSC Publishing, 2010 |
| Edice: |
RSC biomolecular sciences ;
no. 18. |
| Témata: | |
| On-line přístup: |
https://proxy.k.utb.cz/login?url=http://app.knovel.com/hotlink/toc/id:kpNPCDD001/natural_product_chemistry_for_drug_discovery |
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Obsah:
- Natural products as drugs and leads to drugs: The historical perspective / David J. Newman and Gordon M. Cragg
- Chemical space and the difference between natural products and synthetics / Sheo B. Singh and J. Chris Culberson
- Mechanism of action studies / James J. La Clair
- The convention on biological diversity and its impact on natural product research / Geoffrey A. Cordell
- Plants: Revamping the oldest source of medicines with modern science / Giovanni Appendino and Federica Pollastro
- Macromarines: A selective account of the potential of marine sponges, molluscs, soft corals and tunicates as a source of therapeutically important molecular structures / Jennifer Carroll and Phillip Crews
- Microorganisms: Their role in the discovery and development of medicines / Cedric Pearce, Peter Eckard, Iris Gruen-Wollny and Friedrich G. Hansske
- Advances in biological screening for lead discovery / Christian N. Parker, Johannes Ottl, Daniela Gabriel and Ji-Hu Zhang
- Advances in instrumentation, automation, dereplication and prefractionation / Tim S. Bugni, Mary Kay Harper, Malcolm W.B. McCulloch and Emily L. Whitson
- Natural product combinatorial biosynthesis: Promises and realities / Daniel W. Udwary
- A snapshot of natural product-derived compounds in late stage clinical development at the end of 2008 / Mark S. Butler
- From natural product to clinical trials: NPI-0052 (Salinosporamide A), a marine actinomycete-derived
- anticancer agent / Kin S. Lam, G. Kenneth Lloyd, Saskia T.C. Neuteboom, Michael A. Palladino, Kobi M. Sethna, Matthew A. Spear and Barbara C. Potts
- From natural product to clinical trials: Bevirimat, a plant-derived anti-AIDS drug / Keduo Qian, Theodore J. Nitz, Donglei Yu, Graham P. Allaway, Susan L. Morris-Natschke and Kuo-Hsiung Lee
- Daptomycin / Richard H. Baltz
- Micafungin / Akihiko Fujie, Shuichi Tawara and Seiji Hashimoto.
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